Multiple Dose Pharmacokinetics of Paroxetine in Children and Adolescents with Major Depressive Disorder or Obsessive–Compulsive Disorder
نویسندگان
چکیده
منابع مشابه
An international, multicenter, placebo-controlled trial of paroxetine in adolescents with major depressive disorder.
OBJECTIVE The aim of this study was to examine the efficacy, safety, and tolerability of paroxetine in adolescents with unipolar major depression. METHOD Two hundred eighty-six (286) adolescents with unipolar major depression were randomly assigned to receive either paroxetine or placebo for 12 weeks. RESULTS The proportion of Montgomery-Asberg Depression Rating Scale (MADRS) responders (at...
متن کاملFactors affecting discontinuation of initial treatment with paroxetine in panic disorder and major depressive disorder
OBJECTIVE The aims of the present study were to analyze the association between discontinuation of paroxetine (PAX) and the genetic variants of the polymorphism in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) in Japanese patients with panic disorder (PD) and major depressive disorder (MDD). METHODS The 5-HTTLPR genotype was determined by polymerase chain reaction method...
متن کاملIdentifying Early Maladaptive Schema of Patients with Major Depressive Disorder
Cognitive models of depression propose that negative schemas and Early Maladaptive Schema contribute to depressive symptoms. The purpose of this study is to identify the early maladaptive Schema of patients with depression disorder. The method of study is descriptive. Research statistics involves all patients with depression disorder who have come to the c...
متن کاملParoxetine improves social anxiety disorder in children and adolescents.
Wagner KD, Berard R, Stein MB, et al. A multicenter, randomized, double-blind, placebo-controlled trial of paroxetine in children and adolescents with social anxiety disorder. Arch Gen Psychiatry 2004;61:1153–62. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کاملBumetanide in Children and Adolescents with Autism Spectrum Disorder
Introduction: Autism Spectrum Disorder (ASD) is characterized by several impairments in communications and social interactions as well as restricted interests or stereotyped behaviors. Interventions applied for this disorder are based on multi-modal approaches, including pharmacotherapy. No cure or medication has been introduced so far; therefore, there were studies investigating several drugs ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2005
ISSN: 0893-133X,1740-634X
DOI: 10.1038/sj.npp.1300960